Japanese physician Seishu Hanaoka was the father of anaesthesia. He developed and used an orally administered general anaesthetic, a herbal concoction known as "Tsusensan". Hanaoka successfully operated on over 150 patients.
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Japan's Seishu Hanaoka
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The Wife of Seishu Hanaoka
Anaesthesia and Anaesthetics
Hanaoka's technique of breast cancer excision